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Jim Andrews

Scientist

Laboratory for Research in Complex Systems

Education

​Georgetown University School of Medicine
Ph.D Physiology and Biophysics

 

What's your background?

The career of Dr. Andrews has spanned research and development in the public, academic, and private sectors.  In addition to having worked at the FDA as part of the biologics reviewing process, Dr. Andrews has worked to help numerous small molecules and biologics reach marketing approval.  The most salient of which include Enbrel®, Viagra®, Epogen®, and many more.  Dr. Andrews has worked in numerous areas of biological science including a breakthrough in neuroscience where he showed the first rapid actions of steroid hormones in the central nervous system, National Institutes of Health where he researched genetic differences linked to Parkinson’s and Alzheimer’s, infectious disease epidemiology and biostatistics, nanobiotechnology which reversed tumor growth using tissue targeting technology, clinical trial pharmacological and diagnostic assay development and validation, and biomarkers of central nervous system disease affecting the modern warfighter.  

Dr. Andrews earned a Ph.D. from Georgetown University School of Medicine while working on leading methods to inhibit vascular disease including progenitor cell therapy, angiogenesis, and inflammatory mediators.   While at home, he enjoys time with his family doing outdoor activities.   

What's your role at LRC?

I am a visiting Scientist and Advisor.

What trend, breakthrough or discovery are you most excited about?

Application of LRC technologies that support product development due to my involvement.

Research Interests

Dr. Andrews has a diverse set of research interests to include AI/ML, epidemiology, novel CBRN detection methods, novel diagnostics, and novel therapeutic and prophylactic platform technologies.

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Publications
  • Najafi AH, Aghili N, Tilan JU, Andrews JA, Peng X, Lassance-Soares RM, Sood S, Alderman LO, Abe K, Li L, Kolodgie FD, Virmani R, Zukowska Z, Epstein SE, Burnett MS. A new murine model of stress-induced complex atherosclerotic lesions. Dis Model Mech. 2013 Jan 11.

  • Andrews JA, Neises K. Peripheral Blood Mononuclear Cells and Posttraumatic Stress disorder; Peripheral Involvement in a Central Disease. Journal of Neurochemistry. November, 2011.

  • Andrews, JA. Stress, Infection, and Atherosclerosis. (Doctoral Dissertation, Georgetown University School of Medicine, Department of Physiology and Biophysics, June 2008).

  • Najafi AH, Aghili N, Tilan JU, Andrews JA, Peng X, Lassance-Soares RM, Alderman LO, Abe K, Li L, Kolodgie F, Virmani R, Zukowska Z, Epstein SE, Burnett MS. A new murine model of stress-induced complex atherosclerotic lesions. Disease Models and Mechanisms. Jan, 2013.

  • Burnett MS, Lee CW, Kinnaird TD, Stabile E, Durrani S, Dullum MK, Devaney JM, Fishman C, Stamou S, Canos D, Zbinden S, Clavijo LC, Jang GJ, Andrews JA, Zhu J, Epstein SE. The potential role of resistin in atherogenesis. Atherosclerosis. 2005;182(2):241-248.

  • Zbinden S, Clavijo LC, Kantor B, Morsli H, Cortes GA, Andrews JA, Jang GJ, Burnett MS, Epstein SE. Interanimal variability in preexisting collaterals is a major factor determining outcome in experimental angiogenesis trials. Am J Physiol Heart Circ Physiol. 2007;292(4):H1891-H1897.

  • Womble MD, Andrew(s) JA, Crook JJ. 17beta-Estradiol reduces excitatory postsynaptic potential (EPSP) amplitude in rat basolateral amygdala neurons. Neurosci Lett. 2002;331(2):83-86.

  • Devaney JM, Robert SL, Gordish-Dressman H, Kaufman DJ, Adenika RJ, Andrews JA, Jang G, Lindsay J, Pichard AD, Satler LF, Kent KM, Waksman R, Howard BV, Epstein SE, Burnett MS. PPARγ2 Pro12Ala Polymorphism is Associated with Coronary Artery Disease and Myocardial Infarction in Women. The FASEB Journal. 2007;21:lb356.

  • Lovering ME, Heaton KJ, Banderet L, Neises K, Andrews J, Cohen BS. Psychological and physical characteristics of US Marine recruits. Military Psychology 27 (5), 261-275

  • Zbinden S, Clavijo L, Morsli H, Jang GJ, Andrews JA, Stabile E, Kinnaird T. Enhanced angiogenesis: Head to head comparison of freshly aspirated bone marrow vs. bone marrow-derived mesenchymal stem cells in the mouse hind-limb ischemia. Journal of the American College of Cardiology. 45 (3), 377A-377A.

  • JA Andrews, K Andrews, JS Wang, Z Zukowska, MS Burnett-Miller. Chronic stress induces a pro-inflammatory response: Implications for cardiovascular disease. Journal Of The American College Of Cardiology. 2007. 49 (9), 400A-400A.

  • JM Devaney, RS Lindsay, H Gordish-Dressman, DJ Kaufman, RJ Adenika, JA Andrews, et al. PPARγ2

  • Pro12Ala Polymorphism is Associated with Coronary Artery Disease and Myocardial Infarction in Women. The FASEB Journal. 2007. 21 (6), LB76-LB76.

  • JA Andrews, L Kuo, Z Zukowska, MS Burnett-Miller. Stress increases circulating resistin levels; implications for atherosclerosis. The FASEB Journal. 2007. 20 (4), A700-A700.

  • H Morsli, S Zbinden, LC Clavijo, GJ Jang, CW Lee, JM Devaney, Andrews JA. The role of metallothionein as an arteriogenic gene in a murine hind limb ischemia model. Journal Of The American College Of Cardiology. 2005. 45 (3), 377A-377A.

  • S Zbinden, L Clavijo, H Morsli, GJ Jang, JA Andrews, E Stabile, T Kinnaird, et al. Enhanced angiogenesis: Head to head comparison of freshly aspirated bone marrow vs. bone marrow-derived mesenchymal stem cells in the mouse hind-limb ischemia model. Journal Of The American College Of Cardiology. 2005. 45 (3), 377A-377A.